Lassa fever: History, causes, effects, and reduction strategies

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Pathogenesis of Lassa Fever

Lassa virus, an Old World arenavirus (family Arenaviridae), is the etiological agent of Lassa fever, a severe human disease that is reported in more than 100,000 patients annually in the endemic regions of West Africa with mortality rates for hospitalized patients varying between 5-10%. Currently, there are no approved vaccines against Lassa fever for use in humans. Here, we review the publishe...

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Lassa Fever, Nigeria, 2005–2008

To the Editor: Lassa fever affects ≈100,000 persons per year in West Af-rica (1). The disease is caused by Las-sa virus, an arenavirus, and is associated with bleeding and organ failure. The case-fatality rate in hospitalized patients is 10%–20%. The reservoir of the virus is multimammate mice (Mastomys natalensis). Investigations in the 1970s and 1980s pointed to the existence of 3 disease-end...

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ژورنال

عنوان ژورنال: International Journal of One Health

سال: 2020

ISSN: 2455-8931,2455-5673

DOI: 10.14202/ijoh.2020.95-98